吕雅琪，博士，副教授
基本信息
电子邮箱：ylyu07@shutcm.edu.cn
通讯地址：上海市浦东新区蔡伦路1200号
研究方向
中药药剂及新型药物递送系统
2009.09-2013.06, 中国药科大学，基础药学理科基地班，学士
2013.09-2018.06, 中国药科大学，药剂学，博士
工作经历
2018.10-2019.08，香港城市大学，化学系，科研助理
2019.11-2021.10，伦敦玛丽女王大学, 工程与材料科学学院，玛丽居里研究员
2021.12-2025.12，上海中医药大学，中药学院（药剂教研室），讲师
2026.01至今，上海中医药大学，中药学院（药剂教研室），副教授
承担科研项目情况
国家自然科学基金青年基金（C类），“粘附-穿透-跨越”多级眼屏障的功能化肽修饰枸杞子外泌体滴眼剂治疗糖尿病视网膜病变的研究，主持
上海市 “科技创新行动计划”启明星培育（扬帆专项），光热控制超分子水凝胶递送多肽纳米粒抑制眼底病理性新生血管的研究，主持
欧洲委员会地平线2020玛丽居里人才计划，透明质酸主客体修饰水凝胶用于眼部多肽类药物的递送，主持
代表性论文
1、Jing Li, Zi Yan, Dengxuan Mao, Xiumei Liu, Peixin Lee, Yaqi Lyu*, Nianping Feng*. Microneedle technology in the treatment of ocular diseases:Advances and applications. Asian J Pharm Sci, 2026, 101129.
2、Jing Li, Jie Wang, Bingqian Li, Meng Long, Xiumei Liu, Dengxuan Mao, Patrick Pan, Ying Liu, Zimei Wu*, Yaqi Lyu*, Nianping Feng*. Engineering a garlic-derived nanovesicle/microneedle system to boost melanoma immunotherapy through self-amplifying cell death activation and immune remodelling. Chinese Chemical Letters , 2025, 111878.
3、Min Lin, Xiumei Liu, Jing Li, Hong Zou, Jie Wang, Zi Yan, Ying Liu, Yaqi Lyu *, Nianping Feng*. Hybrid NIR-responsive liposome/hydrogel platform mediating chemo-photothermal therapy of retinoblastoma enhanced by quercetin as an adjuvant. Theranostics, 2025, 15(9): 3995-4015
4、Yaqi Lv, Chaoran Xu, Xiangmei Zhao, Chenshi Lin, Xin Yang, Xiaofei Xin, Li Zhang, Chao Qin, Xiaopeng Han, Lei Yang, Wei He*, Lifang Yin*. Nanoplatform assembled from a CD44-targeted prodrug and smart liposomes for dual targeting of tumor microenvironment and cancer cells. ACS Nano, 2018, 12(2): 1519-1536.
5、Yaqi Lyu, Qingqing Xiao, Lifang Yin, Lei Yang*, Wei He*. Potent delivery of an MMP inhibitor to the tumor microenvironment with thermosensitive liposomes for the suppression of metastasis and angiogenesis. Signal Transduction and Targeted Therapy, 2019, 4:26.
6、Yaqi Lv, Xiangmei Zhao, Lidan Zhu, Sijia Li, Qingqing Xiao, Wei He*, Lifang Yin*. Targeting intracellular MMPs efficiently inhibits tumor metastasis and angiogenesis. Theranostics, 2018, 8(10): 2830-2845.
7、Yaqi Lyu，Qingqing Xiao, Yi Li, Yubing Wu, Wei He*, Lifang Yin*. “Locked” cancer cells are more sensitive to chemotherapy. Bioengineering & Translational Medicine, 2019, 4(2): e10130.
8、Yaqi Lyu, Helena Azevedo*. Supramolecular Hydrogels for Protein Delivery in Tissue Engineering. Molecules, 2021, 26(4): 873.
