李 洋

发布者:中药学院发布时间:2021-11-18浏览次数:1139

简介:李洋,助理研究员,2018年毕业于上海中医药大学,获中药学理学博士学位,任上海市药学会青年委员。主要从事天然产物抗肿瘤作用机制研究、中药抗疱疹病毒药效评价等工作。

电子邮箱:liyangsh1991@163.com

近5年(2016-2021)代表性科研成果有:

1) Jiang X#; Li Y#; Feng JL; Nik Nabil WN; Wu R; Lu Y; Liu H; Xi ZC*; Xu HX*; Safranal prevents prostate cancer recurrence by blocking the re-activation of quiescent cancer cells via downregulation of S-phase kinase-associated protein 2, Frontiers in Cell and Developmental Biology (IF=6.684), 2020, 8: 598620.

2) Wong M#; Sun YT#; Xi ZC#; Milazzo G; Poulos R; Bartenhagen C; Bell J; Mayoh C; Ho N; Tee A; Chen XQ; Li Y; Ciaccio R; Liu P; Jiang C; Lan Q; Jayatilleke N; Cheung B; Haber M; Norris M; Zhang X; Marshall G; Wang J; Hüttelmaier S; Fischer M; Wong J; Xu HX*; Perini G; Dong QH; George R; Liu T*; JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma, Nature Communications (IF= 14.919), 2019, 10(1): 3319.

3) Li Y#; Xi ZC#; Chen XQ; Cai SF; Liang C; Wang Z; Li YY; Tan HS; Lao YZ*; Xu HX*; Natural compound Oblongifolin C confers gemcitabine resistance in pancreatic cancer by downregulating Src/MAPK/ERK pathways, Cell Death & Disease (IF= 8.469), 2018, 9(5): 538.

4) Xi Z; Yao M; Li Y; Xie C; Holst J; Liu T; Cai S; Lao Y; Tan H; Xu HX*; Dong Q *; Guttiferone K impedes cell cycle re-entry of quiescent prostate cancer cells via stabilization of FBXW7 and subsequent c-MYC degradation, Cell Death & Disease (IF= 8.469), 2016, 7(6): e2252.

5) 陈小琼; 李洋; 张伊婧;等.Guttiferone K 抑制胰腺癌的体内外活性研究.世界科学技术-中医药现代化, 2017, 19( 2) :241-246

6) 席志超; 姚睦; 李洋; 蔡双璠; 吴蓉; 劳远至; 董其瀚; 徐宏喜*; Guttiferone K抑制静止期前列腺癌细胞重新激活的作用研究, 世界中医药, 2016, 11(7): 1171-1175.