【个人简介】 马越鸣，教授，博士生导师，上海中医药大学教学名师，讲席教授。现任中药学院药理学教研室主任、国家中医药管理局中药药理学三级实验室主任。 1987年皖南医学院硕士毕业，一直从事药理学/中药药理学教学和科研工作。负责承担国家自然科学基金和教育部高校博士点基金、上海市科委、教委、卫生局等多项中药药理学研究课题和上海市重点课程中药药理学教学课题等，负责上海高校创新团队“复方中药药物代谢动力学与创新中药研究团队（2009）”的建设。主编《药理学》、《中药药理学》教材等。负责的项目曾获省自然科学三等奖、上海市医学科技三等奖、上海市科技进步二等奖和中华医学科技二等奖。国内外发表学术论文100多篇，指导硕、博士生获学位40余名。 【学术兼职】 中国药理学会理事及药物代谢专业委员会委员 中华中医药学会实验药理分会常委 上海市药学会药理专业委员会委员 上海市药理学会药代动力学专业委员会委员 【教学课程】 本科《基础药理学》、《中药药理学》、《药代动力学》；研究生《中药药理学专论》。 【科研领域】 中药药物代谢动力学和中药药效评价。 【研究方向】 (1) 中药药物代谢动力学，包括中药体内过程和动力学研究 (2) 基于药动学的中药复方药效物质基础、作用机制和配伍规律研究 (3) 中药抗肝损伤和炎性肠病研究 【近年主要教学论文（通讯作者）】 1.高建平，吴琦，张晓晨，沈伟，沈旭华，马越鸣*.(2021)以学生专业发展为导向的多元混合式中药药理学教学改革。中医药管理杂志.;29(03):17-20 2.石荣，沈旭华，崔红燕，马越鸣*.(2019)仁爱教育融入抗菌药物药理学教学的探索.中医药管理杂志, 27（10）：17-19 3.吴家胜, 沈岚，沈旭华，马越鸣*. (2017) “科研反哺教学”在中药药理学课程实验教学中的应用.中医药管理杂志25（18）：44-45 4.沈云辉，沈旭华，沈伟，马越鸣*(2017)中医药理论指导的中药药理学多样化教学改革.中医药管理杂志. 25（7）：24-26 5.吴家胜，沈旭华，沈云辉，崔红燕，马秉亮，马越鸣*.(2016)高等中医药院校药理学实验教学改革与探索.中医药管理杂志, 24（6）：27-29 【近年主要科研论文（通讯作者）】 Yahang Wang#; Yuanyuan Li#; Hua zhang; Leilei Zhu; Jie Zhong; Jiakai Zeng; Cong Meng; Jiasheng Wu; Tianming Wang; Rong Shi; Weian Yuan; Jian Jiang; Ping Liu*; Yueming Ma*，(2021) Pharmacokinetics-based comprehensive strategy to identify multiple effective components in Huangqi decoction against liver fibrosis，Phytomedicine, 84: 153513. Yuanyuan Li, Haoyu Xue, Su Fang, Guofeng Wang, Yahang Wang, Tianming Wang, Rong Shi, Jiasheng Wu*, Yueming Ma*，(2021) Time-series metabolomics insights into the progressive characteristics of 3, 5-diethoxycarbonyl-1, 4-dihydrocollidine-induced cholestatic liver fibrosis in mice. Journal of Pharmaceutical and Biomedical Analysis. 198: 113986. Jiasheng Wu, Qian Liu, Shanhua Fang, Xing Liu, Min Zheng, Tianming Wang, Hua Zhang, Ping Liu, Hu Zhou*, Yueming Ma*, (2020) Quantitative proteomics reveals the protective effects of Huangqi decoction against acute cholestatic liver injury by inhibiting NF-κB/IL-6/STAT3 signaling pathway，Journal of Proteome Research, 19(2):677-687. Jiasheng Wu, Su Fang, Wenkai Li, Yifei Li, Yuanyuan Li, Tianming Wang, Li Yang, Shaoyong Liu, Zhengtao Wang*, Yueming Ma*. (2020) Metabolomics research on the hepatoprotective effect of cultured bear bile powder in α-naphthylisothiocyanate-induced cholestatic mice, Journal of Chromatography B, 1153, 122269: 1-10. Xiaoshu Sun, Haoyu Xue, Bin Zan, Yining Zhao, Yuanyuan Li, Tianming Wang, Jiasheng Wu, Shaoyong Liu, Zhengtao Wang, Rong Shi*, Li Yang*, Yueming Ma*. (2020) Anti-convulsant effects of cultures bear bile powder in febrile seizure via regulation of neurotransmission and inhibition of neuroinflammation. Journal of Ethnopharmacology, 262:112998. Guofeng Wang , Yuanyuan Li, Rong Shi, Tianming Wang, Yifei Li, Wenkai Li, Min Zheng, Fengbo Fan, Juan Zou, Bin Zan, Jiasheng Wu*, Yueming Ma* . (2020) Yinchenzhufu Decoction protects against alpha-naphthyl isothiocyanate-induced acute cholestatic liver injury in mice by ameliorating disordered bile acid homeostasis and inhibiting inflammatory responses, Journal of Ethnopharmacology, 254:112672.. Wenkai Li, Guofeng Wang, Tianming Wang, Yuanyuan Li, Yifei Li, Xinyi Lu, Wang Yahang Wang, Hua Zhang, Ping Liu, Jiasheng Wu*，Yueming Ma*, (2019) Protective effect of herbal medicine Huangqi decoction against chronic cholestatic liver injury through inhibiting bile acid stimulated inflammation in DDC-induced mice, Phytomedicine, 62:152948. Min Zheng, Yuanyuan Li, Guofeng Wang, Jingyi Jin, Yahang Wang, Tianming Wang, Li Yang, Shaoyong Liu, Jiasheng Wu*, Zhengtao Wang*, Yueming Ma*. (2019) Protective effect of cultured bear bile powder against dimethylnitrosamine-induced hepatic fibrosis in rats. Biomedicine & Pharmacotherapy, 112, 108701. Rong Shi, Zhangyao Xu, Xining Xu, Jingyi Jin, Yining Zhao, Tianming Wang, Yuanyuan Li, Yueming Ma*. (2019) Organic cation transporter and multidrug and toxin extrusion 1 co-mediated interaction between metformin and berberine. European Journal of Pharmaceutical Sciences, 127: 282-290. 李园园，曾佳凯，张学延，马越鸣*，张华，刘平，(2016)黄芪汤对大鼠体内恩替卡韦药动学的影响，药学学报, 51(9): 1429-1435 |
