顾伟梁,副教授,硕士生导师
基本信息
办公电话:021-51322213
电子邮箱:guwl22@shutcm.edu.cn
通讯地址:上海市浦东新区蔡伦路1200号
招生专业
研究方向:中药及复方的药理作用研究
院系名称:中药学院
学位类型:学术学位
专业名称:中药学/100800
2000.09-2004.07, 上海中医药大学, 中药学, 学士
2004.09-2009.07, 上海中医药大学, 中药学, 博士(硕博连读)
任职经历
2009.08-2015.12, 上海中医药大学, 中药学院, 讲师
2015.11-2017.04,哈佛大学医学院, 波士顿儿童医院心血管研究中心,Research Associate
2016.01-至 今, 上海中医药大学, 中药学院, 副教授
获项及荣誉
2009年,上海市优秀毕业生(博士毕业)
2014年,上海中医药大学,“杏林学者-外向型人才”称号。
2017年,上海中医药大学全英语教学竞赛,二等奖及优秀教案奖
2019年,上海市高校外国留学生英语授课示范性课程《中药药理学》,课程负责人
2021年,上海高校市级重点课程建设《药学综合实验》,课程负责人
2022年,上海中医药大学,“金牌教师”称号
2023年,上海中医药大学优秀教学团队,《药学综合实验》课程教学团队负责人
承担科研项目情况
国家自然科学基金青年项目,玄参有效成分安格洛苷C的分离、提取及防治心室重构的作用研究(81202944),主持
上海中医药大学科技发展项目,基于一种大规模平行体内CRISPR筛选模式建立抗心肌肥大中药作用靶标定位的系统(23KFL044),主持
主要代表性成果
Pingzhu Zhou#,Nathan J. VanDusen#, Yanchun Zhang#, Yangpo Cao#, Isha Sethi,Rong Hu,Shuo Zhang,Guangyu Wang, Lincai Ye, Neil Mazumdar, Jian Chen, Xiaoran Zhang, Yuxuan Guo, Bin Li, Qing Ma, Julianna Y. Lee, Weiliang Gu, Guo-Cheng Yuan, Bing Ren, Kaifu Chen*, and William T. Pu*.Dynamic changes in P300 enhancers and enhancer-promoter contacts control mouse cardiomyocyte maturation. Developmental Cell, 2023, 58(10):898-914.(IF=13.417)
Weiwei Wang#, Weiliang Gu#, Chao He, Tong Zhang, Yao Shen*, Yiqiong Pu*. Bioactive Components of Banxia Xiexin Decoction for the Treatment of Gastrointestinal Diseases Based on Flavor-oriented Analysis. Journal of Ethnopharmacology, 2022, 291:115085. (IF=6.656)
Nathan J VanDusen, Julianna Y Lee, Weiliang Gu, Catalina E Butler, Isha Sethi, Yanjiang Zheng, Justin S King, Pingzhu Zhou, Shengbao Suo, Yuxuan Guo, Qing Ma, Guo-Cheng Yuan, William T Pu*. Massively parallel in vivo CRISPR screening identifies RNF20/40 as epigenetic regulators of cardiomyocyte maturation. Nature Communications, 2021,12(1):4442.(IF=17.694)
Nathan J. VanDusen#; Yuxuan Guo#; Weiliang Gu; William T. Pu*; CASAAV: A CRISPR-Based Platform for Rapid Dissection of Gene Function In Vivo, Current Protocols in Molecular Biology, 2017, 120: 31.11.1-31.11.14.
Yuxuan Guo#; Nathan J. VanDusen#; Lina Zhang; Weiliang Gu; Isha Sethi; Silvia Guatimosim; Qing Ma; Blake D. Jardin; Yulan Ai; Donghui Zhang; Biyi Chen; Ang Guo; Guocheng Yuan; Longsheng Song; William T. Pu*; Analysis of cardiac myocyte maturation using CASAAV, a platform for rapid dissection of cardiac myocyte gene function in vivo, Circulation Research, 2017, 120(12): 1874-1888.(IF=23.213)
Weiliang Gu; Changxun Chen*; Xiaoyan Huang; Jianping Gao; The Effect of Angoroside C on Pressure Overload-induced Ventricular Remodeling in Rats, Phytomedicine, 2015, 22(7-8): 705-712.(IF=6.656)
Jian Lv; Weiliang Gu*; Changxun Chen; Effect of gentiopicroside on experimental acute pancreatitis induced by retrograde injection of sodium taurocholate into the biliopancreatic duct in rats, Fitoterapia, 2015, 102: 127-133.(IF=3.204)